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Combined treatment of glibenclamide and CoCl(2) decreases MMP9 expression and inhibits growth in highly metastatic breast cancer

BACKGROUND: To observe the influence of combination treatment with glibenclamide and CoCl(2) on the growth and invasiveness of TA2 breast cancer, and to detect the protein and mRNA expression of MMP9. METHODS: 50 adult female TA2 mice were randomly divided into 5 groups including DMSO control, CoCl(...

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Detalles Bibliográficos
Autores principales: Rong, Zhe, Li, Li, Fei, Fei, Luo, Lailong, Qu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680297/
https://www.ncbi.nlm.nih.gov/pubmed/23714264
http://dx.doi.org/10.1186/1756-9966-32-32