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Activity Determinants of Helical Antimicrobial Peptides: A Large-Scale Computational Study
Antimicrobial peptides (AMPs), produced by a wide range of organisms, have attracted attention due to their potential use as novel antibiotics. The majority of these peptides are cationic and are thought to function by permeabilizing the bacterial membrane, either by making pores or by dissolving it...
Autores principales: | He, Yi, Lazaridis, Themis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680375/ https://www.ncbi.nlm.nih.gov/pubmed/23776672 http://dx.doi.org/10.1371/journal.pone.0066440 |
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