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An Appended Domain Results in an Unusual Architecture for Malaria Parasite Tryptophanyl-tRNA Synthetase

Specific activation of amino acids by aminoacyl-tRNA synthetases (aaRSs) is essential for maintaining fidelity during protein translation. Here, we present crystal structure of malaria parasite Plasmodium falciparum tryptophanyl-tRNA synthetase (Pf-WRS) catalytic domain (AAD) at 2.6 Å resolution in...

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Detalles Bibliográficos
Autores principales:	Khan, Sameena, Garg, Ankur, Sharma, Arvind, Camacho, Noelia, Picchioni, Daria, Saint-Léger, Adélaïde, de Pouplana, Lluís Ribas, Yogavel, Manickam, Sharma, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680381/ https://www.ncbi.nlm.nih.gov/pubmed/23776638 http://dx.doi.org/10.1371/journal.pone.0066224

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