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Molecular Basis for the Dissociation Dynamics of Protein A-Immunoglobulin G1 Complex

Staphylococcus aureus protein A (SpA) is the most popular affinity ligand for immunoglobulin G1 (IgG1). However, the molecular basis for the dissociation dynamics of SpA-IgG1 complex is unclear. Herein, coarse-grained (CG) molecular dynamics (MD) simulations with the Martini force field were used to...

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Detalles Bibliográficos
Autores principales:	Liu, Fu-Feng, Huang, Bo, Dong, Xiao-Yan, Sun, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680412/ https://www.ncbi.nlm.nih.gov/pubmed/23776704 http://dx.doi.org/10.1371/journal.pone.0066935

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