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CD73 Is a Major Regulator of Adenosinergic Signalling in Mouse Brain

CD73 (ecto-5’-nucleotidase) is a cell surface enzyme that regulates purinergic signalling by desphosphorylating extracellular AMP to adenosine. 5′-nucleotidases are known to be expressed in brain, but the expression of CD73 and its putative physiological functions at this location remain elusive. He...

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Detalles Bibliográficos
Autores principales: Kulesskaya, Natalia, Võikar, Vootele, Peltola, Marjaana, Yegutkin, Gennady G., Salmi, Marko, Jalkanen, Sirpa, Rauvala, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680420/
https://www.ncbi.nlm.nih.gov/pubmed/23776700
http://dx.doi.org/10.1371/journal.pone.0066896