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CD73 Is a Major Regulator of Adenosinergic Signalling in Mouse Brain
CD73 (ecto-5’-nucleotidase) is a cell surface enzyme that regulates purinergic signalling by desphosphorylating extracellular AMP to adenosine. 5′-nucleotidases are known to be expressed in brain, but the expression of CD73 and its putative physiological functions at this location remain elusive. He...
Autores principales: | Kulesskaya, Natalia, Võikar, Vootele, Peltola, Marjaana, Yegutkin, Gennady G., Salmi, Marko, Jalkanen, Sirpa, Rauvala, Heikki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680420/ https://www.ncbi.nlm.nih.gov/pubmed/23776700 http://dx.doi.org/10.1371/journal.pone.0066896 |
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