Cargando…
Susceptibility to DNA Damage as a Molecular Mechanism for Non-Syndromic Cleft Lip and Palate
Non-syndromic cleft lip/palate (NSCL/P) is a complex, frequent congenital malformation, determined by the interplay between genetic and environmental factors during embryonic development. Previous findings have appointed an aetiological overlap between NSCL/P and cancer, and alterations in similar b...
Autores principales: | Kobayashi, Gerson Shigeru, Alvizi, Lucas, Sunaga, Daniele Yumi, Francis-West, Philippa, Kuta, Anna, Almada, Bruno Vinícius Pimenta, Ferreira, Simone Gomes, de Andrade-Lima, Leonardo Carmo, Bueno, Daniela Franco, Raposo-Amaral, Cássio Eduardo, Menck, Carlos Frederico, Passos-Bueno, Maria Rita |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680497/ https://www.ncbi.nlm.nih.gov/pubmed/23776525 http://dx.doi.org/10.1371/journal.pone.0065677 |
Ejemplares similares
-
Human Stem Cell Cultures from Cleft Lip/Palate Patients Show Enrichment of Transcripts Involved in Extracellular Matrix Modeling By Comparison to Controls
por: Bueno, Daniela Franco, et al.
Publicado: (2010) -
Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene–environment interaction
por: Alvizi, Lucas, et al.
Publicado: (2023) -
Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects
por: Alvizi, Lucas, et al.
Publicado: (2017) -
Buccinator myomucosal flap for the treatment of velopharyngeal insufficiency in patients with cleft palate and/or lip()()
por: Denadai, Rafael, et al.
Publicado: (2017) -
Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate
por: Howe, Laurence J, et al.
Publicado: (2019)