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The SAX-3 Receptor Stimulates Axon Outgrowth and the Signal Sequence and Transmembrane Domain Are Critical for SAX-3 Membrane Localization in the PDE Neuron of C. elegans
SAX-3, a receptor for Slit in C. elegans, is well characterized for its function in axonal development. However, the mechanism that regulates the membrane localization of SAX-3 and the role of SAX-3 in axon outgrowth are still elusive. Here we show that SAX-3::GFP caused ectopic axon outgrowth, whic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680500/ https://www.ncbi.nlm.nih.gov/pubmed/23776520 http://dx.doi.org/10.1371/journal.pone.0065658 |