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From Bench to Bedside: Review of Gene and Cell-Based Therapies and the Slow Advancement into Phase 3 Clinical Trials, with a Focus on Aastrom’s Ixmyelocel-T
There is a large body of preclinical research demonstrating the efficacy of gene and cellular therapy for the potential treatment of severe (limb-threatening) peripheral arterial disease (PAD), including evidence for growth and transcription factors, monocytes, and mesenchymal stem cells. While prec...
Autores principales: | Bartel, Ronnda L., Booth, Erin, Cramer, Caryn, Ledford, Kelly, Watling, Sharon, Zeigler, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680652/ https://www.ncbi.nlm.nih.gov/pubmed/23456574 http://dx.doi.org/10.1007/s12015-013-9431-x |
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