HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Telomeres are repetitive DNA structures that, together with the shelterin and the CST complex, protect the ends of chromosomes. Telomere shortening is mitigated in stem and cancer cells through the de novo addition of telomeric repeats by telomerase. Telomere elongation requires the delivery of the...

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Detalles Bibliográficos
Autores principales: Kappei, Dennis, Butter, Falk, Benda, Christian, Scheibe, Marion, Draškovič, Irena, Stevense, Michelle, Novo, Clara Lopes, Basquin, Claire, Araki, Masatake, Araki, Kimi, Krastev, Dragomir Blazhev, Kittler, Ralf, Jessberger, Rolf, Londoño-Vallejo, J Arturo, Mann, Matthias, Buchholz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680732/
https://www.ncbi.nlm.nih.gov/pubmed/23685356
http://dx.doi.org/10.1038/emboj.2013.105

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