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Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis
INTRODUCTION: Retinoic acid signaling plays key roles in embryonic development and in maintaining the differentiated status of adult tissues. Recently, the nuclear retinoic acid receptor (RAR) isotypes α, β and γ were found to play specific functions in the expansion and differentiation of the stem...
Autores principales: | Bosch, Almudena, Bertran, Silvina P, Lu, Yongke, Garcia, Avalon, Jones, Alexis M, Dawson, Marcia I, Farias, Eduardo F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680916/ https://www.ncbi.nlm.nih.gov/pubmed/22920668 http://dx.doi.org/10.1186/bcr3247 |
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