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Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells

INTRODUCTION: hPTTG1 (human pituitary tumor-transforming gene 1) is an oncogene overexpressed in breast cancer and several other types of cancer. Increased hPTTG1 expression has been shown to be associated with poor patient outcomes in breast cancer. Although hPTTG1 overexpression plays important ro...

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Detalles Bibliográficos
Autores principales:	Ruan, Jhen-Wei, Liao, Yi-Chu, Lua, Ingrid, Li, Ming-Hsun, Hsu, Chih-Yi, Chen, Ji-Hshiung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680924/ https://www.ncbi.nlm.nih.gov/pubmed/22789011 http://dx.doi.org/10.1186/bcr3226

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