Cargando…

The interaction between ER and NFκB in resistance to endocrine therapy

Endocrine therapy is a commonly used treatment for estrogen receptor (ER)-positive breast cancer. Although endocrine therapy has a favorable outcome in many patients, development of resistance is common. Recent studies have shown that NFκB, a transcription factor regulating a wide variety of cellula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sas, Leen, Lardon, Filip, Vermeulen, Peter B, Hauspy, Jan, Van Dam, Peter, Pauwels, Patrick, Dirix, Luc Y, Van Laere, Steven J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680926/ https://www.ncbi.nlm.nih.gov/pubmed/22963717 http://dx.doi.org/10.1186/bcr3196

Ejemplares similares

Study Assessing the Quality of Quantification of Estrogen Receptor Protein Expression by Immunohistochemistry and Gene Expression in Breast Cancer
por: Leen, Sas, et al.
Publicado: (2014)

A Core Invasiveness Gene Signature Reflects Epithelial-to-Mesenchymal Transition but Not Metastatic Potential in Breast Cancer Cell Lines and Tissue Samples
por: Marsan, Melike, et al.
Publicado: (2014)

Molecular profiles to biology and pathways: a systems biology approach
por: Van Laere, Steven, et al.
Publicado: (2016)

Are Costs of Robot-Assisted Surgery Warranted for Gynecological Procedures?
por: van Dam, Peter, et al.
Publicado: (2011)

Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer
por: Limame, Ridha, et al.
Publicado: (2013)

NF-κB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation
por: Van Laere, S J, et al.
Publicado: (2007)

Array-Based DNA Methylation Profiling for Breast Cancer Subtype Discrimination
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

A dynamic clinical pathway for the treatment of patients with early breast cancer is a tool for better cancer care: implementation and prospective analysis between 2002–2010
por: van Dam, Peter A, et al.
Publicado: (2013)

Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer
por: Oeyen, Steffi, et al.
Publicado: (2020)

Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management
por: van Schooneveld, Eleni, et al.
Publicado: (2015)

Benchmarking and audit of breast units improves quality of care
por: van Dam, P.A., et al.
Publicado: (2013)

Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

Coagulation/fibrinolysis and circulating tumor cells in patients with advanced breast cancer
por: Dirix, Luc Y., et al.
Publicado: (2022)

Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
por: van Schooneveld, Eleni, et al.
Publicado: (2012)

Inflammatory breast carcinoma as a model of accelerated self-metastatic expansion by intravascular growth
por: Vermeulen, P B, et al.
Publicado: (2009)

Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype
por: Van der Auwera, I, et al.
Publicado: (2010)

A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial)
por: Mercier, Carole, et al.
Publicado: (2018)

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment
por: Brouwer, Anja, et al.
Publicado: (2016)

Microarray-Based Oncogenic Pathway Profiling in Advanced Serous Papillary Ovarian Carcinoma
por: Trinh, Xuan Bich, et al.
Publicado: (2011)

Circulating tumour cells in the central and the peripheral venous compartment in patients with metastatic breast cancer
por: Peeters, D J E, et al.
Publicado: (2011)

Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer
por: Dirix, Luc, et al.
Publicado: (2022)

Detection and prognostic significance of circulating tumour cells in patients with metastatic breast cancer according to immunohistochemical subtypes
por: Peeters, D J E, et al.
Publicado: (2014)

Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors
por: Bertucci, François, et al.
Publicado: (2021)

Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
por: Peeters, D J E, et al.
Publicado: (2013)

Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy
por: Baay, Marc, et al.
Publicado: (2011)

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect
por: Jacobs, Julie, et al.
Publicado: (2015)

The role of apoptotic cell death in the radiosensitising effect of gemcitabine
por: Pauwels, B, et al.
Publicado: (2009)

Distinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis
por: Van Laere, S, et al.
Publicado: (2007)

HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques
por: Brouwer, Anja, et al.
Publicado: (2019)

Real-time RT–PCR correlates with immunocytochemistry for the detection of disseminated epithelial cells in bone marrow aspirates of patients with breast cancer
por: Benoy, I H, et al.
Publicado: (2004)

Precision of image-guided spinal stereotactic ablative radiotherapy and impact of positioning variables
por: Billiet, Charlotte, et al.
Publicado: (2022)

Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells
por: Semina, Svetlana E., et al.
Publicado: (2022)

Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-Time Technology and Classic Endpoint Assays
por: Limame, Ridha, et al.
Publicado: (2012)

OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening
por: Deben, Christophe, et al.
Publicado: (2022)

The immune microenvironment characterisation and dynamics in hormone receptor–positive breast cancer before and after neoadjuvant endocrine therapy
por: Oner, Gizem, et al.
Publicado: (2023)

Potential new biomarkers for squamous carcinoma of the uterine cervix
por: van Dam, Peter A, et al.
Publicado: (2018)

Relative microvessel area of the primary tumour, and not lymph node status, predicts the presence of bone marrow micrometastases detected by reverse transcriptase polymerase chain reaction in patients with clinically non-metastatic breast cancer
por: Benoy, Ina H, et al.
Publicado: (2005)

The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients
por: Van der Auwera, I, et al.
Publicado: (2009)

Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study
por: Van den Eynden, G G, et al.
Publicado: (2006)

Outcome and toxicity of hypofractionated image-guided SABR for spinal oligometastases
por: Billiet, Charlotte, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8ranl3q0f0c6mnb5ma43ldklsl