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Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification

INTRODUCTION: Epigenetic events are, along with genetic alteration, important in the development and progression of cancer. Promoter hypermethylation causes gene silencing and is thought to be an early event in carcinogenesis. The role of promoter hypermethylation in male breast cancer has not yet b...

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Detalles Bibliográficos
Autores principales: Kornegoor, Robert, Moelans, Cathy B, Verschuur-Maes, Anoek HJ, Hogenes, Marieke CH, de Bruin, Peter C, Oudejans, Joost J, van Diest, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680933/
https://www.ncbi.nlm.nih.gov/pubmed/22765268
http://dx.doi.org/10.1186/bcr3220