Absence of some common organ-specific and non-organ-specific autoimmunity in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

BACKGROUND: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare autosomal recessive disorder caused by mutations of the autoimmune regulator (AIRE) gene, whose loss of function leads to the escape of self-reactive T cells from the thymus and autoimmunity. APECED patient...

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Detalles Bibliográficos
Autores principales: Kluger, Nicolas, Krohn, Kai, Ranki, Annamari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680957/
https://www.ncbi.nlm.nih.gov/pubmed/23781320
http://dx.doi.org/10.1530/EC-12-0074

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