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Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are present in large numbers in blood of mice and humans with cancer, and they strongly inhibit T-cell and natural killer (NK) cell responses, at young and old age. We found that a highly attenuated bacterium Listeria monocytogenes (Listeria(at))-...

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Detalles Bibliográficos
Autores principales:	Chandra, D, Jahangir, A, Quispe-Tintaya, W, Einstein, M H, Gravekamp, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681012/ https://www.ncbi.nlm.nih.gov/pubmed/23640395 http://dx.doi.org/10.1038/bjc.2013.206

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