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Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma

BACKGROUND: Bcl-xL has an important role in the control of cell death through its inhibition of apoptosis. The aim of this study was to investigate the clinicopathological significance of Bcl-xL in upper urinary tract urothelial carcinoma (UTUC) and the therapeutic effect of targeting Bcl-xL protein...

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Detalles Bibliográficos
Autores principales: Yoshimine, S, Kikuchi, E, Kosaka, T, Mikami, S, Miyajima, A, Okada, Y, Oya, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681018/
https://www.ncbi.nlm.nih.gov/pubmed/23674090
http://dx.doi.org/10.1038/bjc.2013.216