Anthricin Isolated from Anthriscus sylvestris (L.) Hoffm. Inhibits the Growth of Breast Cancer Cells by Inhibiting Akt/mTOR Signaling, and Its Apoptotic Effects Are Enhanced by Autophagy Inhibition

Anthricin (deoxypodophyllotoxin) is a natural product isolated from Anthriscus sylvestris (L.) Hoffm. (Apiaceae). Here, we investigated the effect of anthricin on autophagy and mammalian target of rapamycin (mTOR) signaling as anticancer actions in breast cancer cells. Many studies have supported th...

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Detalles Bibliográficos
Autores principales: Jung, Chang Hwa, Kim, Heemun, Ahn, Jiyun, Jung, Sung Keun, Um, Min Young, Son, Kun-Ho, Kim, Tae Wan, Ha, Tae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681310/
https://www.ncbi.nlm.nih.gov/pubmed/23818925
http://dx.doi.org/10.1155/2013/385219

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