TIMBAL v2: update of a database holding small molecules modulating protein–protein interactions

TIMBAL is a database holding molecules of molecular weight <1200 Daltons that modulate protein–protein interactions. Since its first release, the database has been extended to cover 50 known protein–protein interactions drug targets, including protein complexes that can be stabilized by small mol...

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Detalles Bibliográficos
Autores principales: Higueruelo, Alicia P., Jubb, Harry, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Database Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681332/
https://www.ncbi.nlm.nih.gov/pubmed/23766369
http://dx.doi.org/10.1093/database/bat039
Descripción
Sumario:TIMBAL is a database holding molecules of molecular weight <1200 Daltons that modulate protein–protein interactions. Since its first release, the database has been extended to cover 50 known protein–protein interactions drug targets, including protein complexes that can be stabilized by small molecules with therapeutic effect. The resource contains 14 890 data points for 6896 distinct small molecules. UniProt codes and Protein Data Bank entries are also included. Database URL: http://www-cryst.bioc.cam.ac.uk/timbal

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