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Nanomaterials in the application of tumor vaccines: advantages and disadvantages

Tumor vaccines are a novel approach to the treatment of malignancy, and are attracting the attention of the medical profession. Nanomaterials have significant advantages in the preparation of a tumor vaccine, including their ability to penetrate and target cancer tissue and their antigenic propertie...

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Detalles Bibliográficos
Autores principales: Li, XD, Gao, JY, Yang, Y, Fang, HY, Han, YJ, Wang, XM, Ge, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681402/
https://www.ncbi.nlm.nih.gov/pubmed/23776336
http://dx.doi.org/10.2147/OTT.S41902
Descripción
Sumario:Tumor vaccines are a novel approach to the treatment of malignancy, and are attracting the attention of the medical profession. Nanomaterials have significant advantages in the preparation of a tumor vaccine, including their ability to penetrate and target cancer tissue and their antigenic properties. In this review, we focus on several nanomaterials, ie, carbon nanotubes, nanoemulsions, nanosized aluminum, and nanochitosan. Applications for these nanomaterials in nanovaccines and their biological characteristics, as well as their potential toxicity, are discussed.