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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer
We previously reported MELK (maternal embryonic leucine zipper kinase) as a novel therapeutic target for breast cancer. MELK was also reported to be highly upregulated in multiple types of human cancer. It was implied to play indispensable roles in cancer cell survival and indicated its involvement...
Autores principales: | Chung, Suyoun, Suzuki, Hanae, Miyamoto, Takashi, Takamatsu, Naofumi, Tatsuguchi, Ayako, Ueda, Koji, Kijima, Kyoko, Nakamura, Yusuke, Matsuo, Yo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681500/ https://www.ncbi.nlm.nih.gov/pubmed/23283305 |
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