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Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro
Benzimidazoles act by disrupting microtubule polymerisation and are capable of inducing the formation of micronuclei. Considering the similarities in their mechanisms of action (inhibition of microtubule assembly by binding to the colchicine-binding site on tubulin monomers), combination effects acc...
Autores principales: | Ermler, Sibylle, Scholze, Martin, Kortenkamp, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681538/ https://www.ncbi.nlm.nih.gov/pubmed/23547264 http://dx.doi.org/10.1093/mutage/get019 |
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