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Celecoxib alleviates tamoxifen-instigated angiogenic effects by ROS-dependent VEGF/VEGFR2 autocrine signaling

BACKGROUND: Tamoxifen (TAM) is widely used in the chemotherapy of breast cancer and as a preventive agent against recurrence after surgery. However, extended TAM administration for breast cancer induces increased VEGF levels in patients, promoting new blood vessel formation and thereby limiting its...

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Detalles Bibliográficos
Autores principales:	Kumar, B N Prashanth, Rajput, Shashi, Dey, Kaushik Kumar, Parekh, Aditya, Das, Subhasis, Mazumdar, Abhijit, Mandal, Mahitosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681557/ https://www.ncbi.nlm.nih.gov/pubmed/23731702 http://dx.doi.org/10.1186/1471-2407-13-273

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