Towards better understanding of an industrial cell factory: investigating the feasibility of real-time metabolic flux analysis in Pichia pastoris

BACKGROUND: Novel analytical tools, which shorten the long and costly development cycles of biopharmaceuticals are essential. Metabolic flux analysis (MFA) shows great promise in improving our understanding of the metabolism of cell factories in bioreactors, but currently only provides information p...

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Detalles Bibliográficos
Autores principales: Fazenda, Mariana L, Dias, Joao ML, Harvey, Linda M, Nordon, Alison, Edrada-Ebel, Ruan, LittleJohn, David, McNeil, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681591/
https://www.ncbi.nlm.nih.gov/pubmed/23692918
http://dx.doi.org/10.1186/1475-2859-12-51

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