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Meiosis-Specific Stable Binding of Augmin to Acentrosomal Spindle Poles Promotes Biased Microtubule Assembly in Oocytes

In the oocytes of many animals including humans, the meiotic spindle assembles without centrosomes. It is still unclear how multiple pathways contribute to spindle microtubule assembly, and whether they are regulated differently in mitosis and meiosis. Augmin is a γ-tubulin recruiting complex which...

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Detalles Bibliográficos
Autores principales: Colombié, Nathalie, Głuszek, A. Agata, Meireles, Ana M., Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681601/
https://www.ncbi.nlm.nih.gov/pubmed/23785300
http://dx.doi.org/10.1371/journal.pgen.1003562