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Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

BACKGROUND: Deficiency in tuberin results in activation the mTOR pathway and leads to accumulation of cell matrix proteins. The mechanisms by which tuberin regulates fibrosis in kidney angiomyolipomas (AMLs) of tuberous sclerosis patients are not fully known. METHOD: In the present study, we investi...

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Detalles Bibliográficos
Autores principales:	Liang, Sitai, Cuevas, Gabriela, Tizani, Shaza, Salas, Tiffanie, Liu, Huijuan, Li, Baojie, Habib, Samy L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681649/ https://www.ncbi.nlm.nih.gov/pubmed/23705901 http://dx.doi.org/10.1186/1476-4598-12-49

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