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High Trans-ethnic Replicability of GWAS Results Implies Common Causal Variants
Genome-wide association studies (GWAS) have detected many disease associations. However, the reported variants tend to explain small fractions of risk, and there are doubts about issues such as the portability of findings over different ethnic groups or the relative roles of rare versus common varia...
Autores principales: | Marigorta, Urko M., Navarro, Arcadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681663/ https://www.ncbi.nlm.nih.gov/pubmed/23785302 http://dx.doi.org/10.1371/journal.pgen.1003566 |
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