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PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation
PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however, the basis for the anti-metastasic activities resulting from PARP inhibition remains unknown. PARP inhibitors may also act as modulators of tum...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681683/ https://www.ncbi.nlm.nih.gov/pubmed/23785295 http://dx.doi.org/10.1371/journal.pgen.1003531 |