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Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes
We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation. Phosphorylation of XSSH at multiple sites within the tail domain occurs just after germinal vesicle...
Autores principales: | Iwase, Shohei, Sato, Ryuhei, De Bock, Pieter-Jan, Gevaert, Kris, Fujiki, Saburo, Tawada, Toshinobu, Kuchitsu, Miyako, Yamagishi, Yuka, Ono, Shoichiro, Abe, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681698/ https://www.ncbi.nlm.nih.gov/pubmed/23615437 http://dx.doi.org/10.1091/mbc.E12-12-0851 |
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