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Costly Class-1 integrons and the domestication of the the functional integrase
Class-1 integrons play an important role in the emergence and spread of antimicrobial resistance determinants. In a recent study we showed that host fitness was dramatically reduced following acquisition of these elements. These fitness costs were due to the presence of an active integrase and we su...
Autores principales: | Harms, Klaus, Starikova, Irina, Johnsen, Pål J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681742/ https://www.ncbi.nlm.nih.gov/pubmed/23914313 http://dx.doi.org/10.4161/mge.24774 |
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