Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses

To identify new regulators of antiviral innate immunity, we completed the first genome-wide gene silencing screen assessing the transcriptional response at the interferon-β (IFNB1) promoter following Sendai virus (SeV) infection. We now report a novel link between WNT signaling pathway and the modul...

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Detalles Bibliográficos
Autores principales: Baril, Martin, Es-Saad, Salwa, Chatel-Chaix, Laurent, Fink, Karin, Pham, Tram, Raymond, Valérie-Ann, Audette, Karine, Guenier, Anne-Sophie, Duchaine, Jean, Servant, Marc, Bilodeau, Marc, Cohen, Éric, Grandvaux, Nathalie, Lamarre, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681753/
https://www.ncbi.nlm.nih.gov/pubmed/23785285
http://dx.doi.org/10.1371/journal.ppat.1003416

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