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Norepinephrine Drives Persistent Activity in Prefrontal Cortex via Synergistic α1 and α2 Adrenoceptors

Optimal norepinephrine levels in the prefrontal cortex (PFC) increase delay-related firing and enhance working memory, whereas stress-related or pathologically high levels of norepinephrine are believed to inhibit working memory via α1 adrenoceptors. However, it has been shown that activation of Gq-...

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Detalles Bibliográficos
Autores principales:	Zhang, Zizhen, Cordeiro Matos, Steven, Jego, Sonia, Adamantidis, Antoine, Séguéla, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681776/ https://www.ncbi.nlm.nih.gov/pubmed/23785477 http://dx.doi.org/10.1371/journal.pone.0066122

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