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Induced Pluripotent Stem Cell-Derived Cardiac Progenitors Differentiate to Cardiomyocytes and Form Biosynthetic Tissues

The mammalian heart has little capacity to regenerate, and following injury the myocardium is replaced by non-contractile scar tissue. Consequently, increased wall stress and workload on the remaining myocardium leads to chamber dilation, dysfunction, and heart failure. Cell-based therapy with an au...

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Detalles Bibliográficos
Autores principales: Christoforou, Nicolas, Liau, Brian, Chakraborty, Syandan, Chellapan, Malathi, Bursac, Nenad, Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681781/
https://www.ncbi.nlm.nih.gov/pubmed/23785459
http://dx.doi.org/10.1371/journal.pone.0065963