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Induced Pluripotent Stem Cell-Derived Cardiac Progenitors Differentiate to Cardiomyocytes and Form Biosynthetic Tissues

The mammalian heart has little capacity to regenerate, and following injury the myocardium is replaced by non-contractile scar tissue. Consequently, increased wall stress and workload on the remaining myocardium leads to chamber dilation, dysfunction, and heart failure. Cell-based therapy with an au...

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Detalles Bibliográficos
Autores principales:	Christoforou, Nicolas, Liau, Brian, Chakraborty, Syandan, Chellapan, Malathi, Bursac, Nenad, Leong, Kam W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681781/ https://www.ncbi.nlm.nih.gov/pubmed/23785459 http://dx.doi.org/10.1371/journal.pone.0065963

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