PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Mutations in PIK3CA are present in 10 to 15% of colorectal carcinomas. We aimed to examine how PIK3CA mutations relate to other molecular alterations in colorectal carcinoma, to pathologic phenotype and survival. PIK3CA mutation testing was carried out using direct sequencing on 757 incident tumors...

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Detalles Bibliográficos
Autores principales: Rosty, Christophe, Young, Joanne P., Walsh, Michael D., Clendenning, Mark, Sanderson, Kristy, Walters, Rhiannon J., Parry, Susan, Jenkins, Mark A., Win, Aung Ko, Southey, Melissa C., Hopper, John L., Giles, Graham G., Williamson, Elizabeth J., English, Dallas R., Buchanan, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681782/
https://www.ncbi.nlm.nih.gov/pubmed/23785428
http://dx.doi.org/10.1371/journal.pone.0065479

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