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Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes

The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the healthy immune response the original equilibrium is eventually restored through counter-regulatory mechanisms. In certain autoimmune diseases howe...

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Detalles Bibliográficos
Autores principales:	Larsson, Helena Elding, Jönsson, Ida, Lernmark, Åke, Ivarsson, Sten, Radtke, Jared R., Hampe, Christiane S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681789/ https://www.ncbi.nlm.nih.gov/pubmed/23785410 http://dx.doi.org/10.1371/journal.pone.0065173

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