Th Cells Promote CTL Survival and Memory via Acquired pMHC-I and Endogenous IL-2 and CD40L Signaling and by Modulating Apoptosis-Controlling Pathways

Involvement of CD4(+) helper T (Th) cells is crucial for CD8(+) cytotoxic T lymphocyte (CTL)-mediated immunity. However, CD4(+) Th’s signals that govern CTL survival and functional memory are still not completely understood. In this study, we assessed the role of CD4(+) Th cells with acquired antige...

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Detalles Bibliográficos
Autores principales: Umeshappa, Channakeshava Sokke, Xie, Yufeng, Xu, Shulin, Nanjundappa, Roopa Hebbandi, Freywald, Andrew, Deng, Yulin, Ma, Hong, Xiang, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681805/
https://www.ncbi.nlm.nih.gov/pubmed/23785406
http://dx.doi.org/10.1371/journal.pone.0064787

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