Immunization of Aged Pigs with Attenuated Pseudorabies Virus Vaccine Combined with CpG Oligodeoxynucleotide Restores Defective Th1 Immune Responses

BACKGROUND AND AIMS: Attempts to immunize aged subjects often result in the failure to elicit a protective immune response. Murine model studies have shown that oligonucleotides containing CpG motifs (CpG ODN) can stimulate immune system in aged mice as effectively as in young mice. Since many physi...

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Detalles Bibliográficos
Autores principales: Ming, Feiping, Yang, Jun, Chu, Pinpin, Ma, Miaopeng, Shi, Juqing, Cai, Haiming, Huang, Chaoyuan, Li, Huazhou, Jiang, Zhenggu, Wang, Houguang, Wang, Weifang, Zhang, Shuiqing, Zhang, Linghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681863/
https://www.ncbi.nlm.nih.gov/pubmed/23785433
http://dx.doi.org/10.1371/journal.pone.0065536

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