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A Pro-Inflammatory Role of C5L2 in C5a-Primed Neutrophils for ANCA-Induced Activation

BACKGROUND: The complement system is crucial for the development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In particular, C5a and its receptor on neutrophils, CD88, play a central role. The functional role of the second receptor of C5a, C5L2, remains unclear. In the...

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Detalles Bibliográficos
Autores principales:	Hao, Jian, Wang, Chen, Yuan, Jun, Chen, Min, Zhao, Ming-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681967/ https://www.ncbi.nlm.nih.gov/pubmed/23785491 http://dx.doi.org/10.1371/journal.pone.0066305

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