Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close K(ATP) Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans

In non-obese diabetic (NOD) mice, diabetes incidence is reduced by a gluten-free diet. Gluten peptides, such as the compound gliadin, can cross the intestinal barrier and may directly affect pancreatic beta cells. We investigated the effects of enzymatically-digested gliadin in NOD mice, INS-1E cell...

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Detalles Bibliográficos
Autores principales: Dall, Morten, Calloe, Kirstine, Haupt-Jorgensen, Martin, Larsen, Jesper, Schmitt, Nicole, Josefsen, Knud, Buschard, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681969/
https://www.ncbi.nlm.nih.gov/pubmed/23785500
http://dx.doi.org/10.1371/journal.pone.0066474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681969/
https://www.ncbi.nlm.nih.gov/pubmed/23785500
http://dx.doi.org/10.1371/journal.pone.0066474

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