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Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close K(ATP) Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans
In non-obese diabetic (NOD) mice, diabetes incidence is reduced by a gluten-free diet. Gluten peptides, such as the compound gliadin, can cross the intestinal barrier and may directly affect pancreatic beta cells. We investigated the effects of enzymatically-digested gliadin in NOD mice, INS-1E cell...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681969/ https://www.ncbi.nlm.nih.gov/pubmed/23785500 http://dx.doi.org/10.1371/journal.pone.0066474 |