Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides

B13 is a ceramide analogue and apoptosis inducer with potent cytotoxic activity. A series of arylpropyl sulfonamide analogues of B13 were evaluated for their cytotoxicity using MTT assays in prostate cancer PC-3 and leukemia HL-60 cell lines. Some compounds (4, 9, 13, 14, 15, and 20) showed stronger...

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Detalles Bibliográficos
Autores principales: Hwang, Yu Jin, Park, Sang Min, Yim, Chul Bu, Im, Chaeuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682085/
https://www.ncbi.nlm.nih.gov/pubmed/23776401
http://dx.doi.org/10.4196/kjpp.2013.17.3.237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682085/
https://www.ncbi.nlm.nih.gov/pubmed/23776401
http://dx.doi.org/10.4196/kjpp.2013.17.3.237

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