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Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin

The purpose of this study was to investigate the effects of fluvastatin on the pharmacokinetics of repaglinide in rats. The effect of fluvastatin on P-glycoprotein and CYP3A4 activity was evaluated. The pharmacokinetic parameters and blood glucose concentrations were also determined after oral and i...

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Detalles Bibliográficos
Autores principales:	Lee, Chong-Ki, Choi, Jun-Shik, Bang, Joon Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682086/ https://www.ncbi.nlm.nih.gov/pubmed/23776402 http://dx.doi.org/10.4196/kjpp.2013.17.3.245

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