Unexpected properties of NADP-dependent secondary alcohol dehydrogenase (ADH-1) in Trichomonas vaginalis and other microaerophilic parasites

Our previous observation that NADP-dependent secondary alcohol dehydrogenase (ADH-1) is down-regulated in metronidazole-resistant Trichomonas vaginalis isolates prompted us to further characterise the enzyme. In addition to its canonical enzyme activity as a secondary alcohol dehydrogenase, a pronou...

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Detalles Bibliográficos
Autores principales: Leitsch, David, Williams, Catrin F., Lloyd, David, Duchêne, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682184/
https://www.ncbi.nlm.nih.gov/pubmed/23578856
http://dx.doi.org/10.1016/j.exppara.2013.03.034

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