Cargando…

Membrane Binding and Self-Association of the Epsin N-Terminal Homology Domain

Epsin possesses a conserved epsin N-terminal homology (ENTH) domain that acts as a phosphatidylinositol 4,5-bisphosphate‐lipid‐targeting and membrane‐curvature‐generating element. Upon binding phosphatidylinositol 4,5‐bisphosphate, the N-terminal helix (H(0)) of the ENTH domain becomes structured an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Chun-Liang, Jao, Christine C., Lyman, Edward, Gallop, Jennifer L., Peter, Brian J., McMahon, Harvey T., Langen, Ralf, Voth, Gregory A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682188/ https://www.ncbi.nlm.nih.gov/pubmed/22922484 http://dx.doi.org/10.1016/j.jmb.2012.08.010

Ejemplares similares

Coarse-Grained Simulations Suggest the Epsin N-Terminal Homology Domain Can Sense Membrane Curvature without Its Terminal Amphipathic Helix
por: Belessiotis-Richards, Alexis, et al.
Publicado: (2020)

Epsin15 Homology Domains: Role in the Pathogenesis of Pulmonary Arterial Hypertension
por: Predescu, Dan, et al.
Publicado: (2018)

EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking
por: Mills, Ian G., et al.
Publicado: (2003)

A requirement for epsin in mitotic membrane and spindle organization
por: Liu, Zhonghua, et al.
Publicado: (2009)

Spatial Control of Epsin-induced Clathrin Assembly by Membrane Curvature
por: Holkar, Sachin S., et al.
Publicado: (2015)

Single Particle Fluorescence Burst Analysis of Epsin Induced Membrane Fission
por: Brooks, Arielle, et al.
Publicado: (2015)

Binding mechanism of the matrix domain of HIV-1 gag on lipid membranes
por: Monje-Galvan, Viviana, et al.
Publicado: (2020)

Complimentary action of structured and unstructured domains of epsin supports clathrin-mediated endocytosis at high tension
por: Joseph, Jophin G., et al.
Publicado: (2020)

Biomechanical Role of Epsin in Influenza A Virus Entry
por: Joseph, Jophin G., et al.
Publicado: (2022)

Cooperativity of membrane-protein and protein–protein interactions control membrane remodeling by epsin 1 and affects clathrin-mediated endocytosis
por: Kroppen, Benjamin, et al.
Publicado: (2020)

Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking
por: Hirst, Jennifer, et al.
Publicado: (2015)

Epsin and Sla2 form assemblies through phospholipid interfaces
por: Garcia-Alai, Maria M., et al.
Publicado: (2018)

Computational modeling suggests binding-induced expansion of Epsin disordered regions upon association with AP2
por: Jagannathan, N. Suhas, et al.
Publicado: (2021)

Epsin 1 Undergoes Nucleocytosolic Shuttling and Its Eps15 Interactor Nh(2)-Terminal Homology (Enth) Domain, Structurally Similar to Armadillo and Heat Repeats, Interacts with the Transcription Factor Promyelocytic Leukemia Zn(2)+ Finger Protein (Plzf)
por: Hyman, Joel, et al.
Publicado: (2000)

Epsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer Progression
por: Tessneer, Kandice L., et al.
Publicado: (2013)

Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses
por: Kyung, Jae Won, et al.
Publicado: (2016)

Epsin-mediated degradation of IP3R1 fuels atherosclerosis
por: Dong, Yunzhou, et al.
Publicado: (2020)

Structural analysis of a new carotenoid-binding protein: the C-terminal domain homolog of the OCP
por: Dominguez-Martin, Maria Agustina, et al.
Publicado: (2020)

Endocytic Adaptor Protein Epsin Is Elevated in Prostate Cancer and Required for Cancer Progression
por: Tessneer, Kandice L., et al.
Publicado: (2013)

Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development
por: Chang, Baojun, et al.
Publicado: (2015)

Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling
por: Dong, Yunzhou, et al.
Publicado: (2021)

Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase
por: Anselmi, Massimiliano, et al.
Publicado: (2020)

Epsin 1 Promotes Synaptic Growth by Enhancing BMP Signal Levels in Motoneuron Nuclei
por: Vanlandingham, Phillip A., et al.
Publicado: (2013)

The Dynamic Interactions of a Multitargeting Domain in Ameloblastin Protein with Amelogenin and Membrane
por: Kegulian, Natalie C., et al.
Publicado: (2023)

Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain
por: Liefhebber, Jolanda MP, et al.
Publicado: (2009)

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits
por: Messa, Mirko, et al.
Publicado: (2014)

EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis()
por: Mori, Jinichi, et al.
Publicado: (2017)

Epsin 3 potentiates the NF-κB signaling pathway to regulate apoptosis in breast cancer
por: Wu, Qianxue, et al.
Publicado: (2022)

The N-terminal domain of apolipoprotein B-100: structural characterization by homology modeling
por: Al-Ali, Hassan, et al.
Publicado: (2007)

Drosophila Tel2 Is Expressed as a Translational Fusion with EpsinR and Is a Regulator of Wingless Signaling
por: Lee, Ji-Hoon, et al.
Publicado: (2012)

Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte
por: Li, Ling, et al.
Publicado: (2016)

Ca(2+)-saturated calmodulin binds tightly to the N-terminal domain of A-type fibroblast growth factor homologous factors
por: Mahling, Ryan, et al.
Publicado: (2021)

Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily
por: Lenoir, Marc, et al.
Publicado: (2015)

Systematic simulation of the interactions of pleckstrin homology domains with membranes
por: Le Huray, Kyle I. P., et al.
Publicado: (2022)

Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains
por: Boucrot, Emmanuel, et al.
Publicado: (2012)

Regulated Membrane Localization of Tiam1, Mediated by the NH(2)-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH(2)-terminal Kinase Activation
por: Michiels, Frits, et al.
Publicado: (1997)

C-Terminal β9-Strand of the Cyclic Nucleotide-Binding Homology Domain Stabilizes Activated States of Kv11.1 Channels
por: Ng, Chai Ann, et al.
Publicado: (2013)

The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue
por: Legg, Max S.G., et al.
Publicado: (2022)

Epsins Regulate Mouse Embryonic Stem Cell Exit from Pluripotency and Neural Commitment by Controlling Notch Activation
por: Cardano, Marina, et al.
Publicado: (2019)

Cooperative regulation of endocytic vesicle transport by yeast Eps15-like protein Pan1p and epsins
por: Yoshida, Nao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ronk7k4fgu64gc2nof1nojs6dq