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Oxygen-induced hypercapnia in COPD: myths and facts

During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through the 'hypoxic drive' mechanism and can be dangerous. This mindset frequently results in the reluctance of clinicians to administer oxy...

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Detalles Bibliográficos
Autores principales: Abdo, Wilson F, Heunks, Leo MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682248/
https://www.ncbi.nlm.nih.gov/pubmed/23106947
http://dx.doi.org/10.1186/cc11475
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author Abdo, Wilson F
Heunks, Leo MA
author_facet Abdo, Wilson F
Heunks, Leo MA
author_sort Abdo, Wilson F
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description During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through the 'hypoxic drive' mechanism and can be dangerous. This mindset frequently results in the reluctance of clinicians to administer oxygen to hypoxemic patients with COPD. However, this fear is not based on evidence in the literature. Here, we will review the impact and pathophysiology of oxygen-induced hypercapnia in patients with acute exacerbation of COPD and recommend a titrated oxygen management.
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spelling pubmed-36822482013-10-29 Oxygen-induced hypercapnia in COPD: myths and facts Abdo, Wilson F Heunks, Leo MA Crit Care Viewpoint During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through the 'hypoxic drive' mechanism and can be dangerous. This mindset frequently results in the reluctance of clinicians to administer oxygen to hypoxemic patients with COPD. However, this fear is not based on evidence in the literature. Here, we will review the impact and pathophysiology of oxygen-induced hypercapnia in patients with acute exacerbation of COPD and recommend a titrated oxygen management. BioMed Central 2012 2012-10-29 /pmc/articles/PMC3682248/ /pubmed/23106947 http://dx.doi.org/10.1186/cc11475 Text en Copyright ©2012 BioMed Central Ltd
spellingShingle Viewpoint
Abdo, Wilson F
Heunks, Leo MA
Oxygen-induced hypercapnia in COPD: myths and facts
title Oxygen-induced hypercapnia in COPD: myths and facts
title_full Oxygen-induced hypercapnia in COPD: myths and facts
title_fullStr Oxygen-induced hypercapnia in COPD: myths and facts
title_full_unstemmed Oxygen-induced hypercapnia in COPD: myths and facts
title_short Oxygen-induced hypercapnia in COPD: myths and facts
title_sort oxygen-induced hypercapnia in copd: myths and facts
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682248/
https://www.ncbi.nlm.nih.gov/pubmed/23106947
http://dx.doi.org/10.1186/cc11475
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