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Therapeutic efficacy of CXCR3 blockade in an experimental model of severe sepsis

INTRODUCTION: In our previous studies we demonstrated that CXC chemokine receptor 3 (CXCR3) participates in the regulation of lymphocyte trafficking during cecal ligation and puncture (CLP)-induced sepsis. In this study, we evaluated the effects of treatment with anti-CXCR3 immunoglobulin (IgG) and...

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Detalles Bibliográficos
Autores principales:	Herzig, Daniela S, Guo, Yin, Fang, Geping, Toliver-Kinsky, Tracy E, Sherwood, Edward R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682267/ https://www.ncbi.nlm.nih.gov/pubmed/22992408 http://dx.doi.org/10.1186/cc11642

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