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Metformin overdose causes platelet mitochondrial dysfunction in humans

INTRODUCTION: We have recently demonstrated that metformin intoxication causes mitochondrial dysfunction in several porcine tissues, including platelets. The aim of the present work was to clarify whether it also causes mitochondrial dysfunction (and secondary lactate overproduction) in human platel...

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Detalles Bibliográficos
Autores principales:	Protti, Alessandro, Lecchi, Anna, Fortunato, Francesco, Artoni, Andrea, Greppi, Noemi, Vecchio, Sarah, Fagiolari, Gigliola, Moggio, Maurizio, Comi, Giacomo Pietro, Mistraletti, Giovanni, Lanticina, Barbara, Faraldi, Loredana, Gattinoni, Luciano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682281/ https://www.ncbi.nlm.nih.gov/pubmed/23034133 http://dx.doi.org/10.1186/cc11663

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