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Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature

Primary malignant mesothelioma (MM) of spermatic cord is extremely rare. We presented two malignant mesotheliomas involving the spermatic cords; one was primary, one secondary. The secondary one represented the direct involvement by a peritoneal MM. No occupational exposure to asbestos was identifie...

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Autores principales: Meng, Xianmin, Guzzo, Thomas J., Bing, Zhanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682456/
https://www.ncbi.nlm.nih.gov/pubmed/23772303
http://dx.doi.org/10.4081/rt.2013.e4
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author Meng, Xianmin
Guzzo, Thomas J.
Bing, Zhanyong
author_facet Meng, Xianmin
Guzzo, Thomas J.
Bing, Zhanyong
author_sort Meng, Xianmin
collection PubMed
description Primary malignant mesothelioma (MM) of spermatic cord is extremely rare. We presented two malignant mesotheliomas involving the spermatic cords; one was primary, one secondary. The secondary one represented the direct involvement by a peritoneal MM. No occupational exposure to asbestos was identified in either patient. Both of them presented with a painless inguinal mass. Microscopically the primary MM was epithelioid type with tumor nests infiltrating adjacent adipose tissue, while the secondary MM grew in mixed type. No tumor necrosis was seen in the primary MM, while extensive necrosis was seen in the secondary one. Rare mitotic figure was seen in the primary MM while the mitosis in the secondary tumor was brisk, and with atypical mitosis. Immunohistochemically the tumor cells were positive for calretinin and CK5/6 and negative for BER-EP4 and BRST3 in both cases. The reported cases of primary MM from spermatic cord in English literature were briefly reviewed.
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spelling pubmed-36824562013-06-14 Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature Meng, Xianmin Guzzo, Thomas J. Bing, Zhanyong Rare Tumors Case Report Primary malignant mesothelioma (MM) of spermatic cord is extremely rare. We presented two malignant mesotheliomas involving the spermatic cords; one was primary, one secondary. The secondary one represented the direct involvement by a peritoneal MM. No occupational exposure to asbestos was identified in either patient. Both of them presented with a painless inguinal mass. Microscopically the primary MM was epithelioid type with tumor nests infiltrating adjacent adipose tissue, while the secondary MM grew in mixed type. No tumor necrosis was seen in the primary MM, while extensive necrosis was seen in the secondary one. Rare mitotic figure was seen in the primary MM while the mitosis in the secondary tumor was brisk, and with atypical mitosis. Immunohistochemically the tumor cells were positive for calretinin and CK5/6 and negative for BER-EP4 and BRST3 in both cases. The reported cases of primary MM from spermatic cord in English literature were briefly reviewed. PAGEPress Publications 2013-03-26 /pmc/articles/PMC3682456/ /pubmed/23772303 http://dx.doi.org/10.4081/rt.2013.e4 Text en ©Copyright X. Meng et al., 2013 This work is licensed under a Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0). Licensee PAGEPress, Italy
spellingShingle Case Report
Meng, Xianmin
Guzzo, Thomas J.
Bing, Zhanyong
Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title_full Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title_fullStr Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title_full_unstemmed Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title_short Malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
title_sort malignant mesotheliomas in spermatic cords: reports of two cases and a brief review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682456/
https://www.ncbi.nlm.nih.gov/pubmed/23772303
http://dx.doi.org/10.4081/rt.2013.e4
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