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Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity
Recent work has demonstrated the importance of post-transcriptional gene regulation in toxic responses. In the present study, we used two rat models to investigate mRNA translation in the liver following xenobiotic-induced toxicity. By combining polysome profiling with genomic methodologies, we were...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682751/ https://www.ncbi.nlm.nih.gov/pubmed/23586759 http://dx.doi.org/10.1042/BJ20130049 |